Sugammadex and Hormonal Contraception
During anesthesia we give drugs to relax your muscles. We give drugs to reverse this effect before you wake up. One of these drugs is called sugammadex. It interacts with the hormone progesterone.
- You may receive sugammadex as part of your anesthetic.
- Sugammadex may reduce how well hormone contraceptives work.
- This may increase the chance of pregnancy.
What should I do?
- Please tell your anesthesiologist about any hormone contraception you take
| Situation | Advice |
|---|---|
| Oral hormone contraceptives
• Progesterone only oral contraceptive “mini pill” • combined oral contraceptive “pill” |
Take your pill as normal on the morning of surgery
If you receive sugammadex, follow the missed pill advice in the pill package leaflet. |
| Other hormonal contraceptives
• contraceptive implant • hormonal intra-uterine system (IUS) - Mirena coil, Kyleena, Liletta • Depo-provera (injection) • vaginal ring |
If you receive sugammadex, you should use barrier contraception for 7 days after surgery.
Follow the advice in the package leaflet of the contraceptive product. |
Please speak to your anesthesiologist for more information.
CCAD_Sugammadex and hormonal contraception_V1_ (27 April 2023)
© Copyright 27/04/2023 Cleveland Clinic Abu Dhabi. All rights reserved.
This information is provided by Cleveland Clinic Abu Dhabi, part of Mubadala Healthcare, and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition. For additional health information, you may visit www.clevelandclinicabudhabi.ae. This document was last reviewed on: 27/04/2023. Index #00267.
References
Williams, R. and Bryant, H. (2018), Sugammadex advice for women of childbearing age. Anaesthesia, 73: 133-134. https://doi.org/10.1111/anae.14176 (access 01/04/2023).
Schaller S, Fink H. Sugammadex as a reversal agent for neuromuscular block: an evidence-based review. Core Evidence 2013; 8: 57–67.
Bailey CR. Sugammadex: when should we be giving it? Anaesthesia 2017; 72: 1170–5.
Nag K, Singh DR, Shetti AN, Kumar H, Sivashanmugam T, Parthasarathy S. Sugammadex: a revolutionary drug in neuromuscular pharmacology. Anaesthetic Essays and Researches 2013; 7: 302–6.
European Medicines Agency. Bridion. Summary of Product characteristics. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000885/WC500052310.pdf (accessed 01/04/2023).
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