Neurolytic Blocks for Cancer-Related Pain

What is a neurolytic block?

A neurolytic block, also known as neurolysis or chemical neurolysis, is a procedure used to alleviate severe cancer-related pain.

The procedure involves injecting a chemical into the nerve which destroys the nerve or nerve plexus, and then disrupts the transmission of pain signals along specific nerves.

A neurolytic block is a complementary, novel procedure that reduces the need for opioid medications and improves the quality of life significantly for the patient.

The advanced procedure is provided by a multidisciplinary team of experts at Cleveland Clinic Abu Dhabi, who employ a streamlined and coordinated approach to managing complex pain management cases.

When are neurolytic blocks used?

Neurolytic blocks are particularly effective in managing cancer-related pain that starts in specific nerve pathways. The procedure can be applied to nerves in various areas of the body, including the abdominal region (e.g., celiac plexus block), the chest (e.g., thoracic paravertebral block), and the pelvis (e.g., hypogastric plexus block).

Which patients can benefit from neurolytic blocks?

Neurolytic blocks are offered to cancer patients who are experiencing severe localized or regional pain which is significantly impacting their quality of life.

These patients may have advanced-stage cancers or metastases that cause chronic, uncontrolled pain. Candidates for this procedure have typically tried conventional pain management methods, such as oral medications and radiation therapy, without achieving adequate pain relief.

Neurolytic blocks are considered when other pain management options have not been successful or are not feasible.

What are the benefits of neurolytic blocks?

Neurolytic blocks offer many benefits to cancer patients:

• Effective pain relief: Neurolytic blocks provide targeted and efficient pain relief, offering patients relief from severe pain that may not respond adequately to traditional pain management methods.
• Improved quality of life: By significantly reducing or eliminating pain, neurolytic blocks enable patients to regain their mobility and engage in daily activities with increased comfort and independence.
• Minimally invasive: The procedure is minimally invasive, involving needle injections, and can often be performed on an outpatient basis. This reduces the risk of complications and shortens the recovery time for patients.
• Reduced pain medication dependency: Neurolytic blocks can reduce the need for strong pain medications, potentially decreasing the risk of side effects and dependency issues associated with long-term opioid use.
• Community impact: Effective pain management with neurolytic blocks improves the overall well-being of patients and their families, easing the burden on caregivers and healthcare resources. This leads to a positive impact on the community by promoting better patient outcomes and optimizing healthcare utilization.

What does the procedure involve?

Patients receiving neurolytic blocks will be seen in an outpatient clinic. They will be required to fast for at least 6 hours prior to the procedure.

At the time of the procedure, a sedative will be given. Using fluoroscopy or ultrasound, the target nerve is identified, and a needle administers the block.

After the procedure, the patient will be briefly monitored during recovery and will be able to go home the same day. A follow-up appointment will be scheduled at the clinic in 2-4 weeks.