Gastrointestinal Disorders

What are the functional gastrointestinal disorders?

Functional disorders are those in which the gastrointestinal (GI) tract looks normal but doesn't work properly. They are the most common problems affecting the GI tract (including the colon and rectum). Constipation and irritable bowel syndrome (IBS) are two common examples.

Many factors may upset the GI tract and its motility (or ability to keep moving), including:

• Eating a diet low in fiber
• Not enough exercise
• Traveling or other changes in routine
• Eating large amounts of dairy products
• Stress
• Resisting the urge to have a bowel movement
• Resisting the urge to have bowel movements due to pain from hemorrhoids
• Overusing laxatives (stool softeners) that, over time, weaken the bowel muscles
• Taking antacid medicines containing calcium or aluminum
• Taking certain medicines (especially antidepressants, iron pills, and strong pain medicines such as narcotics)
• Pregnancy

Constipation

Constipation means it is hard to have a bowel movement (or pass stools), they are infrequent (less than three times a week), or incomplete. Constipation is usually caused by inadequate roughage or fiber in the diet, or a disruption of the regular routine or diet.

Constipation causes a person to strain during a bowel movement. It may cause small, hard stools and sometimes anal problems such as fissures and hemorrhoids. Constipation is rarely the sign of a more serious medical condition.

You can treat your constipation by:

• Increasing the amount of fiber you eat
• Exercise regularly
• Moving your bowels when you have the urge (resisting the urge causes constipation)

If these treatment methods don't work, laxatives are a temporary solution. Note that the overuse of laxatives can actually make symptoms of constipation worse. Always follow the instructions on the laxative medicine, as well as the advice of your doctor.

Irritable bowel syndrome (IBS)

Irritable bowel syndrome (also called spastic colon, irritable colon, or nervous stomach) is a condition in which the colon muscle contracts more often than in people without IBS. Certain foods, medicines, and emotional stress are some factors that can trigger IBS.

Symptoms of IBS include:

• Abdominal pain and cramps
• Excess gas
• Bloating
• Change in bowel habits such as harder, looser, or more urgent stools than normal
• Alternating constipation and diarrhea

Treatment includes:

• Avoiding caffeine
• Increasing fiber in the diet
• Monitoring which foods trigger IBS (and avoiding these foods)
• Minimizing stress or learning different ways to cope with stress
• Sometimes taking medicines as prescribed by your healthcare provider

What are structural gastrointestinal disorders?

Structural disorders are those in which the bowel looks abnormal and doesn't work properly. Sometimes, the structural abnormality needs to be removed surgically. Common examples of structural GI disorders include hemorrhoids, diverticular disease, colon polyps, colon cancer, and inflammatory bowel disease.

Anal disorders

Hemorrhoids

Hemorrhoids are swollen blood vessels that line the anal opening. They are caused by chronic excess pressure from straining during a bowel movement, persistent diarrhea, or pregnancy.

There are two types of hemorrhoids: internal and external.

Internal hemorrhoids

Internal hemorrhoids are blood vessels on the inside of the anal opening. When they fall down into the anus as a result of straining, they become irritated and start to bleed. Ultimately, internal hemorrhoids can fall down enough to prolapse (sink or stick) out of the anus.

Treatment includes:

• Improving bowel habits (such as avoiding constipation, not straining during bowel movements, and moving your bowels when you have the urge).
• Your doctor using elastic bands to eliminate the vessels.
• Your doctor removing them surgically. Surgery is needed only for a small number of patients with very large, painful, and persistent hemorrhoids.

External hemorrhoids

External hemorrhoids are veins that lie just under the skin on the outside of the anus. Sometimes, after straining, the external hemorrhoidal veins burst and a blood clot forms under the skin. This very painful condition is called a pile.

Treatment includes removing the clot and vein under local anesthesia and /or removing the hemorrhoid itself.

Anal fissures

Anal fissures are splits or cracks in the lining of the anal opening. The most common cause of an anal fissure is the passage of very hard or watery stools. The crack in the anal lining exposes the underlying muscles that control the passage of stool through the anus and out of the body. An anal fissure is one of the most painful problems because the exposed muscles become irritated from exposure to stool or air, and leads to intense burning pain, bleeding, or spasm after bowel movements.

Initial treatment for anal fissures includes pain medicine, dietary fiber to reduce the occurrence of large, bulky stools, and sitz baths (sitting in a few inches of warm water). If these treatments don't relieve pain, surgery might be needed to repair the sphincter muscle.

Perianal abscesses

Perianal abscesses can occur when the tiny anal glands that open on the inside of the anus become blocked, and the bacteria always present in these glands cause an infection. When pus develops, an abscess forms. Treatment includes draining the abscess, usually under local anesthesia in the doctor's office.

Anal fistula

An anal fistula often follows drainage of an abscess and is an abnormal tube-like passageway from the anal canal to a hole in the skin near the opening of the anus. Body wastes traveling through the anal canal are diverted through this tiny channel and out through the skin, causing itching and irritation. Fistulas also cause drainage, pain, and bleeding. They rarely heal by themselves and usually need surgery to drain the abscess and close off the fistula.

Other perianal infections

Sometimes the skin glands near the anus become infected and need to be drained. Just behind the anus, abscesses can form that contains a small tuft of hair at the back of the pelvis (called a pilonidal cyst).

Sexually transmitted diseases that can affect the anus include anal warts, herpes, AIDS, chlamydia, and gonorrhea.

Diverticular disease

Diverticulosis is the presence of small outpouchings (diverticula) in the muscular wall of the large intestine that form in weakened areas of the bowel. They usually occur in the sigmoid colon, the high-pressure area of the lower large intestine.

Diverticular disease is very common and occurs in 10% of people over age 40 and in 50% of people over age 60 in Western cultures. It is often caused by too little roughage (fiber) in the diet. Diverticulosis rarely causes symptoms.

Complications of diverticular disease happen in about 10% of people with outpouchings. They include infection or inflammation (diverticulitis), bleeding, and obstruction. Treatment of diverticulitis includes antibiotics, increased fluids, and a special diet. Surgery is needed in about half the patients who have complications to remove the involved segment of the colon.

Colon polyps and cancer

About 101 colorectal cancer cases were documented in Abu Dhabi in 2011. This makes colorectal cancer the second most common form of cancer after breast cancer. Studies show that it also affects men more than more in the Abu Dhabi region. Fortunately, with advances in early detection and treatment, colorectal cancer is one of the most curable forms of the disease. By using a variety of screening tests, it is possible to prevent, detect, and treat the disease long before symptoms appear.

By using a variety of screening tests, it is possible to prevent, detect, and treat the disease long before symptoms appear.

The importance of screening

Almost all colorectal cancers begin as polyps, benign (non-cancerous) growths in the tissues lining the colon and rectum. Cancer develops when these polyps grow and abnormal cells develop and start to invade surrounding tissue. Removal of polyps can prevent the development of colorectal cancer. Almost all precancerous polyps can be removed painlessly using a flexible lighted tube called a colonoscope. If not caught in the early stages, colorectal cancer can spread throughout the body. More advanced cancer requires more complicated surgical techniques.

Most early forms of colorectal cancer do not cause symptoms, which makes screening especially important. When symptoms do occur, cancer might already be quite advanced. Symptoms include blood on or mixed in with the stool, a change in normal bowel habits, narrowing of the stool, abdominal pain, weight loss, or constant tiredness.

Most cases of colorectal cancer are detected in one of four ways:

• By screening people at average risk for colorectal cancer beginning at age 50
• By screening people at higher risk for colorectal cancer (for example, those with a family history or a personal history of colon polyps or cancer)
• By investigating the bowel in patients with symptoms
• A chance finding at a routine check-up

Early detection is the best chance for a cure.

Colitis

There are several types of colitis, conditions that cause an inflammation of the bowel. These include:

• Infectious colitis
• Ulcerative colitis (cause not known)
• Crohn's disease (cause not known)
• Ischemic colitis (caused by not enough blood going to the colon)
• Radiation colitis (after radiotherapy)

Colitis causes diarrhea, rectal bleeding, abdominal cramps, and urgency (frequent and immediate need to empty the bowels). Treatment depends on the diagnosis, which is made by colonoscopy and biopsy.

Can gastrointestinal disease be prevented?

Many diseases of the colon and rectum can be prevented or minimized by maintaining a healthy lifestyle, practicing good bowel habits, and submitting to cancer screening.

Colonoscopy is recommended for average-risk patients at age 50. If you have a family history of colorectal cancer or polyps, colonoscopy may be recommended at a younger age. Typically, colonoscopy is recommended 10 years younger than the affected family member. (For example, if your brother was diagnosed with colorectal cancer or polyps at age 45, you should begin screening at age 35).

If you have symptoms of colorectal cancer you should consult your doctor right away. Common symptoms include:

• A change in normal bowel habits
• Blood on or in the stool that is either bright or dark
• Unusual abdominal or gas pains
• Very narrow stool
• A feeling that the bowel has not emptied completely after passing stool
• Unexplained weight loss
• Fatigue