This handout is a summary of information to help you understand and safely take your medication. You may have unique healthcare needs not addressed in this handout. Be sure to ask your doctor or pharmacist about your individual needs.
Propafenone (proe-pa-FEEN-none) is used to treat patients who have irregular heartbeats (arrhythmias) and to keep your heart beating normally. It acts on the heart muscle to improve the heart’s rhythm.
Propafenone is usually taken three times a day. You may start taking this medication in the hospital so your healthcare team can closely watch how the medication affects you. It is important to carefully follow the instructions on the prescription label. Ask your pharmacist or doctor to explain anything about the medication that you do not understand. Take the medication exactly as your doctor tells you to.
It is important to keep a steady level of propafenone in your body. Take the medication at the same times each day. NEVER stop taking this medication without first talking with your doctor. If you suddenly stop taking propafenone, your heartbeat may become irregular.
Propafenone comes in tablet form. The prescription label tells you how many tablets to take each time you take your medication. Take only that amount. You can take propafenone with or without food. If you have any questions about propafenone or refilling your prescription, ask your pharmacist.
Foods and salt substitutes that contain potassium can affect the way propafenone works in your body. Grapefruit and grapefruit juice should be avoided, as it may increase serum concentrations of this medication.
Ask your doctor about changes you may need to make to your diet.
Before you start taking propafenone, tell your doctor:
If you take any of these medications, also tell your pharmacist.
If you need to have surgery, including oral surgery, tell your surgeon that you take propafenone.
Take the missed dose if you remember it within 4 hours. If 4 or more hours pass after your scheduled dose, skip the missed dose and take your next regular dose. Do not take a double dose of propafenone.
Side effects are not common. But, the following side effects are possible:
If you have these symptoms, immediately stop taking propafenone and call your doctor.
If you are concerned about any other side effects you have that you think could be caused by propafenone, call your doctor.
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This information is provided by the Cleveland Clinic and is not intended to replace the medical advice of your doctor or healthcare provider. Please consult your healthcare provider for advice about a specific medical condition.
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